Reconstruction of an extensive gouty tophus ulceration at the wrist using a dermal matrix and autologous skin graft: A case report

The staged reconstruction protocol, which combines dermal substitution with autologous skin grafting, delivers durable soft tissue coverage and functional preservation in complex wrist gout ulcerations. This approach represents a less morbid and technically feasible alternative to traditional flap surgery, particularly in high-risk patients with multiple comorbidities. Excellent mid-term outcomes were observed, including 24-month recurrence-free survival.

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Publication Details

Journal
JPRAS Open
Published
2026-01-05
DOI
https://doi.org/10.1016/j.jpra.2025.12.027
Primary Topic
Gout, Hyperuricemia, Uric Acid
Type
article
Field-Weighted Citation Impact
0.00
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article

Reconstruction of an extensive gouty tophus ulceration at the wrist using a dermal matrix and autologous skin graft: A case report

Z Q Wang, Jian Lin, Tian-Hao Zhang, Jian-Hong Huang
JPRAS Open
Gout, Hyperuricemia, Uric Acid
article

Reconstruction of an extensive gouty tophus ulceration at the wrist using a dermal matrix and autologous skin graft: A case report

Z Q Wang, Jian Lin, Tian-Hao Zhang, Jian-Hong Huang
article en

Abstract

The staged reconstruction protocol, which combines dermal substitution with autologous skin grafting, delivers durable soft tissue coverage and functional preservation in complex wrist gout ulcerations. This approach represents a less morbid and technically feasible alternative to traditional flap surgery, particularly in high-risk patients with multiple comorbidities. Excellent mid-term outcomes were observed, including 24-month recurrence-free survival.

JPRAS OpenVol. 48
Shanghai University of Medicine and Health Sciences (CN)
Openalex Percentile: Top 98%
Gout, Hyperuricemia, Uric Acid
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