Tandem Extracorporeal Blood Purification/Support Therapies in Critically Ill Children: A Literature Review

Tandem EBP/STs remain an emerging but incompletely standardized intervention in pediatric critical care. While they offer potential benefits such as improved procedural efficiency and reduced vascular access requirements, their use is limited by heterogeneous protocols, off-label application, and risk of complications. Efforts toward developing standardized guidelines, enhancing multidisciplinary training, and establishing multicenter registries may help optimize their safe and effective use in critically ill children.

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Publication Details

Journal
Critical Care Medicine
Published
2025-11-21
DOI
https://doi.org/10.1097/ccm.0000000000006939
Primary Topic
Mechanical Circulatory Support Devices
Type
article
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article

Tandem Extracorporeal Blood Purification/Support Therapies in Critically Ill Children: A Literature Review

Timothy E. Bunchman, Minh N. Tran, Dana Y. Fuhrman, Patricia Raimer et al.
Critical Care Medicine
Mechanical Circulatory Support Devices
article

Tandem Extracorporeal Blood Purification/Support Therapies in Critically Ill Children: A Literature Review

Timothy E. Bunchman, Minh N. Tran, Dana Y. Fuhrman, Patricia Raimer, Jonathan H. Pelletier, Matthew L. Paden, Aadil Kakajiwala, Poyyapakkam Srivaths, Parth Shirode, Khalid Alhasan, Angelina Dixon, Tara Beck, Rupesh Raina
article en

Abstract

Tandem EBP/STs remain an emerging but incompletely standardized intervention in pediatric critical care. While they offer potential benefits such as improved procedural efficiency and reduced vascular access requirements, their use is limited by heterogeneous protocols, off-label application, and risk of complications. Efforts toward developing standardized guidelines, enhancing multidisciplinary training, and establishing multicenter registries may help optimize their safe and effective use in critically ill children.

Critical Care MedicineVol. 54(1)
Summa Health System (US), Cleveland Clinic (US), Children's National (US), University of Pittsburgh (US), Baylor College of Medicine (US), King Saud University (SA), Akron Children's Hospital (US), University of Pittsburgh Medical Center (US), Children's Healthcare of Atlanta (US), Cleveland Clinic Akron General (US), Children's Hospital of Richmond at VCU (US), University of Colorado Anschutz Medical Campus (US), University of Colorado Denver (US), Northeast Ohio Medical University (US)
Good health and well-being
Openalex Percentile: Top 40%
Mechanical Circulatory Support Devices
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Tandem Extracorporeal Blood Purification/Support Therapies in Critically Ill Children: A Literature Review — Timothy E. Bunchman, Minh N. Tran, et al. · Critical Care Medicine (2025) | TGRS Research Map | TGRS