Molecular insights into the antimicrobial and cardiometabolic functions of Lactobacillus crispatus isolated from the reproductive tract microbiota of Indian women
L. crispatus confers diverse health benefits through pathogen resistance functions and modulation of host metabolic pathways. These findings support its potential as a novel biotherapeutic for preventing and managing hepatic and cardiometabolic disorders, extending its therapeutic relevance beyond reproductive health.
Authors
- Shriram Mahajan (ORCID: https://orcid.org/0000-0002-3322-820X)
- Nitya Wadhwa (ORCID: https://orcid.org/0000-0002-9435-1842)
- N. C. J. Packia Lekshmi
- Yashwant Kumar (ORCID: https://orcid.org/0000-0001-5128-3336)
- Pooja Dhiman (ORCID: https://orcid.org/0009-0007-7160-7087)
- S. Banerjee (ORCID: https://orcid.org/0000-0002-0044-0984)
- Rajni Yadav (ORCID: https://orcid.org/0000-0002-6754-2862)
- Pallavi Mudgal
- Shinjini Bhatnagar
- Sudheer Arava
- Manjari Gupta
- Bhabatosh Das
- Daizee Talukdar
Institutions
- Translational Health Science and Technology Institute (IN)
- National Institute of Pharmaceutical Education and Research (IN)
- All India Institute of Medical Sciences (IN)
Publication Details
- Journal
- Journal of Biomedical Science
- Published
- 2026-01-05
- DOI
- https://doi.org/10.1186/s12929-025-01207-w
- Citations
- 1
- Primary Topic
- Probiotics and Fermented Foods
- Type
- article
- Field-Weighted Citation Impact
- 30.02
Funders
- Department of Biotechnology, Ministry of Science and Technology, India
- Translational Health Science and Technology Institute