<scp>CEST MRI</scp> Processing Pipeline in Pilot Study of Alzheimer's Disease Patients
Our proposed pipeline enables robust data analysis using either MTR<sub>asym</sub> or multi-pool Lorentzian quantification approaches. The results suggest feasibility for detecting CEST differences between CI and CN groups in brain regions previously implicated in AD, motivating future validation in larger cohorts.
Authors
- Ivan Dimitrov (ORCID: https://orcid.org/0000-0003-2686-6884)
- Brendan Kelley (ORCID: https://orcid.org/0000-0002-3440-5191)
- Jochen Keupp (ORCID: https://orcid.org/0000-0003-2129-1153)
- Elena Vinogradov (ORCID: https://orcid.org/0000-0003-4607-4147)
- Alexander Asturias (ORCID: https://orcid.org/0000-0001-8656-2749)
- Fang Yu (ORCID: https://orcid.org/0000-0001-9913-1331)
- Elizabeth M. Davenport
Institutions
- Southwestern Medical Center (US)
- Philips (United States) (US)
- Advanced Imaging Research (United States) (US)
- Philips (Germany) (DE)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- Magnetic Resonance in Medicine
- Published
- 2026-01-04
- DOI
- https://doi.org/10.1002/mrm.70240
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Southwestern Medical Foundation
- National Institutes of Health