Genomic characterization of Neisseria meningitidis from urethritis in a sentinel surveillance hospital, China

This study provides the first genomic characterization of urogenital colonized Nm strains in Guangzhou, China. The phylogenetic analysis further confirms that two foreign Nm urogenital lineages have circulated in China, which are associated with decreased penicillin susceptibility. It is essential to strengthen species identification capabilities and routinely conduct antimicrobial susceptibility testing to monitor the spread of urogenital Nm strains.

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Publication Details

Journal
BMC Microbiology
Published
2026-01-05
DOI
https://doi.org/10.1186/s12866-025-04649-2
Primary Topic
Bacterial Infections and Vaccines
Type
article
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article

Genomic characterization of Neisseria meningitidis from urethritis in a sentinel surveillance hospital, China

Zhengqiang He, Bo Fu, Ligang Yang, Joseph D. Tucker et al.
BMC Microbiology
Bacterial Infections and Vaccines
article

Genomic characterization of Neisseria meningitidis from urethritis in a sentinel surveillance hospital, China

Zhengqiang He, Bo Fu, Ligang Yang, Joseph D. Tucker, Xingzhong Wu, Xiaolin Qin, Xiaohui Zhang, Wujian Ke
article en

Abstract

This study provides the first genomic characterization of urogenital colonized Nm strains in Guangzhou, China. The phylogenetic analysis further confirms that two foreign Nm urogenital lineages have circulated in China, which are associated with decreased penicillin susceptibility. It is essential to strengthen species identification capabilities and routinely conduct antimicrobial susceptibility testing to monitor the spread of urogenital Nm strains.

BMC MicrobiologyVol. 26(1)
University of North Carolina at Chapel Hill (US), Chinese Center For Disease Control and Prevention (CN), Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Chinese Academy of Medical Sciences Dermatology Hospital (CN), Nanjing Municipal Center for Disease Control And Prevention (CN), Southern Medical University (CN), Nanjing Medical University (CN)
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Openalex Percentile: Top 98%
Bacterial Infections and Vaccines
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Genomic characterization of Neisseria meningitidis from urethritis in a sentinel surveillance hospital, China — Zhengqiang He, Bo Fu, et al. · BMC Microbiology (2026) | TGRS Research Map | TGRS