IL-6 as a Potential Sensitive Serum Biomarker in Stevens-johnson Syndrome/Toxic Epidermal Necrolysis: Two Case Reports

Although different cytokines and serum markers have been proposed for the diagnosis of severe cutaneous adverse reactions (SCAR) like SJS/TEN, they are still experimental. We were the first to use IL-6 measurement as a helpful biomarker in the diagnosis and therapeutic management.

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Journal
Recent Advances in Inflammation & Allergy Drug Discovery
Published
2026-01-02
DOI
https://doi.org/10.2174/0127722708411671251129222134
Primary Topic
Drug-Induced Adverse Reactions
Type
article
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article

IL-6 as a Potential Sensitive Serum Biomarker in Stevens-johnson Syndrome/Toxic Epidermal Necrolysis: Two Case Reports

E. Nettis, Gianfranco Calogiuri, Angela Filoni, Caterina Foti et al.
Recent Advances in Inflammation & Allergy Drug Discovery
Drug-Induced Adverse Reactions
article

IL-6 as a Potential Sensitive Serum Biomarker in Stevens-johnson Syndrome/Toxic Epidermal Necrolysis: Two Case Reports

E. Nettis, Gianfranco Calogiuri, Angela Filoni, Caterina Foti, Emiliano Sordi, Lucia Pietroleonardo, Francesca Petrachi, Ester Sofia Congedo, Maurizio Congedo, Gianluigi Conte
article en

Abstract

Although different cytokines and serum markers have been proposed for the diagnosis of severe cutaneous adverse reactions (SCAR) like SJS/TEN, they are still experimental. We were the first to use IL-6 measurement as a helpful biomarker in the diagnosis and therapeutic management.

Recent Advances in Inflammation & Allergy Drug DiscoveryVol. 20
Università Campus Bio-Medico (IT), Ospedale Vito Fazzi (IT), University of Bari Aldo Moro (IT)
Good health and well-being
Openalex Percentile: Top 96%
Drug-Induced Adverse Reactions
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IL-6 as a Potential Sensitive Serum Biomarker in Stevens-johnson Syndrome/Toxic Epidermal Necrolysis: Two Case Reports — E. Nettis, Gianfranco Calogiuri, et al. · Recent Advances in Inflammation & Allergy Drug Discovery (2026) | TGRS Research Map | TGRS