Effects of phenylephrine and norepinephrine with restrictive infusion on oxygenation during one-lung ventilation for lung surgery: a randomized controlled trial
Combining phenylephrine with restrictive infusion during OLV improved oxygenation by increasing PaO<sub>2</sub>, decreasing Qs/Qt, and raising endothelin and COX-2 levels in lung tissue, thereby enhancing the HPV effect.
Authors
- Yi Liu
- Xiangjie Liu
- Jiaxin Li (ORCID: https://orcid.org/0009-0000-4211-4821)
- Yongzhe Liu
- Longhe Xu
Institutions
- Third Hospital of Changsha (CN)
- Jinzhou Medical University (CN)
Publication Details
- Journal
- Annals of Medicine
- Published
- 2026-01-05
- DOI
- https://doi.org/10.1080/07853890.2025.2611655
- Primary Topic
- Respiratory Support and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00