Assessment of sub-chronic toxicity and anti-aging effects of a solid self-microemulsifying drug delivery system of <i>Kaempferia parviflora</i> extract in a D-galactose-induced rat model

KPS-SMEDDS was well-tolerated in rats and exerted protective effects against D-galactose-induced aging. These findings support its potential as a safe, natural anti-aging agent and highlight the value of formulation enhancement in traditional herbal medicine.

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Publication Details

Journal
Pharmaceutical Biology
Published
2026-01-05
DOI
https://doi.org/10.1080/13880209.2025.2606956
Primary Topic
Antioxidants, Aging, Portulaca oleracea
Type
article
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article

Assessment of sub-chronic toxicity and anti-aging effects of a solid self-microemulsifying drug delivery system of Kaempferia parviflora extract in a D-galactose-induced rat model

Peera Tabboon, BUNGORN SRIPANIDKULCHAI, Catheleeya Mekjaruskul, Waraporn Sakaew et al.
Pharmaceutical Biology
Antioxidants, Aging, Portulaca oleracea
article

Assessment of sub-chronic toxicity and anti-aging effects of a solid self-microemulsifying drug delivery system of Kaempferia parviflora extract in a D-galactose-induced rat model

Peera Tabboon, BUNGORN SRIPANIDKULCHAI, Catheleeya Mekjaruskul, Waraporn Sakaew, Choowadee Pariwatthanakun, Somsuda Somintara, Tawut Rudtanatip, Sarunya Tuntiyasawasdikul, Jenjiralai Phanphak
article en

Abstract

KPS-SMEDDS was well-tolerated in rats and exerted protective effects against D-galactose-induced aging. These findings support its potential as a safe, natural anti-aging agent and highlight the value of formulation enhancement in traditional herbal medicine.

Pharmaceutical BiologyVol. 64(1)
Mahasarakham University (TH), Khon Kaen University (TH)
Good health and well-being
Openalex Percentile: Top 97%
Antioxidants, Aging, Portulaca oleracea
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