Future prospects for image-derived input function in molecular imaging quantification with the 7 T MR-BrainPET insert
Positron emission tomography (PET) and magnetic resonance imaging (MRI) offer complementary information about the human brain in health and disease. The simultaneous 7 T MR-BrainPET insert enables molecular imaging quantification beyond the current limits. Here we present the current status of the field highlighting PET/MR synergies for the image-derived input function (IDIF). We also discuss promising applications that will benefit from these advancements, as well the challenges to be addressed in the near future.
Authors
- J. Scheins (ORCID: https://orcid.org/0000-0003-3474-430X)
- Changhoon Choi (ORCID: https://orcid.org/0000-0001-8123-1510)
- Cláudia Régio Brambilla (ORCID: https://orcid.org/0000-0002-3735-8511)
- Christoph Lerche (ORCID: https://orcid.org/0000-0003-2749-2108)
- Usman Khalid (ORCID: https://orcid.org/0000-0002-6710-4686)
- Julia Hilgers
- Jörg Mauler (ORCID: https://orcid.org/0000-0003-4937-0355)
- Tornike Kikacheishvili
- N. Jon Shah
- Ninea Anasovi
Institutions
- Forschungszentrum Jülich (DE)
- Agricultural University of Georgia (GE)
- Jülich Aachen Research Alliance (DE)
- Georgian American University (GE)
- RWTH Aachen University (DE)
Publication Details
- Journal
- Frontiers in Neuroscience
- Published
- 2026-01-05
- DOI
- https://doi.org/10.3389/fnins.2025.1725728
- Primary Topic
- Medical Imaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsche Forschungsgemeinschaft