Sex steroid hormones, gonadotropins, and risk of testicular germ cell tumors: results from the STEED study
These results suggest that gonadotropin disruption may be a critical event in the development of TGCT. Further examination of upstream and downstream metabolites in the hormone pathways may help elucidate the underlying mechanism that distinguishes men who develop TGCT from men who do not.
Authors
- Britton Trabert (ORCID: https://orcid.org/0000-0002-1539-6090)
- Frank Z. Stanczyk (ORCID: https://orcid.org/0000-0002-3607-121X)
- N RIFAI
- Aika Wojt
- Andrea A. Almeida
- Zeni Wu
- Barry I Graubard
- Katherine A Mcglynn
Institutions
- University of Southern California (US)
- Henry M. Jackson Foundation (US)
- Boston Children's Hospital (US)
- Uniformed Services University of the Health Sciences (US)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Huntsman Cancer Institute (US)
- Peking Union Medical College Hospital (CN)
- Boston Children's Museum (US)
- Department of Health and Human Services (US)
Publication Details
- Journal
- JNCI Journal of the National Cancer Institute
- Published
- 2025-12-31
- DOI
- https://doi.org/10.1093/jnci/djaf376
- Primary Topic
- Testicular diseases and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00