A Multimodal Diagnostic Algorithm for Focal Knee Chondral Defects: Correlating Clinical Tests, Musculoskeletal Ultrasound, and MRI-Based ICRS Grading
Symptom severity alone does not reliably distinguish between ICRS Grade 3 and Grade 4 focal chondral lesions. McMurray's test, while not cartilage-specific, was associated with lesion complexity due to its reflection of concomitant meniscal pathology rather than cartilage depth itself. Accordingly, McMurray's test should be interpreted as an indirect clinical indicator of combined osteochondral-meniscal involvement. The integration of targeted clinical tests (Wilson's and McMurray's), MSK-US and MRI-based ICRS grading may support clinical orientation and preoperative risk stratification, forming a pragmatic diagnostic framework rather than a definitive staging tool.
Authors
- Robert Gherghel
- Paul Dan Sîrbu (ORCID: https://orcid.org/0000-0003-2806-0649)
- Elena Rezuş (ORCID: https://orcid.org/0000-0002-8175-2583)
- Daniel Mădălin Coja (ORCID: https://orcid.org/0009-0007-9953-393X)
- Sonia Gabriela Neagu (ORCID: https://orcid.org/0009-0000-3064-5537)
- Carmina Liana Mușat
- Ilie Onu
- Corneliu Mircea Codreanu
- Daniel Andrei Iordan
- Georgiana Bianca Constantin
Institutions
- Lucian Blaga University of Sibiu (RO)
- Grigore T. Popa University of Medicine and Pharmacy (RO)
- "Dunarea de Jos" University of Galati (RO)
- Microelectronica (Romania) (RO)
Publication Details
- Journal
- Life
- Published
- 2026-01-05
- DOI
- https://doi.org/10.3390/life16010080
- Primary Topic
- Musculoskeletal synovial abnormalities and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00