A Multimodal Diagnostic Algorithm for Focal Knee Chondral Defects: Correlating Clinical Tests, Musculoskeletal Ultrasound, and MRI-Based ICRS Grading

Symptom severity alone does not reliably distinguish between ICRS Grade 3 and Grade 4 focal chondral lesions. McMurray's test, while not cartilage-specific, was associated with lesion complexity due to its reflection of concomitant meniscal pathology rather than cartilage depth itself. Accordingly, McMurray's test should be interpreted as an indirect clinical indicator of combined osteochondral-meniscal involvement. The integration of targeted clinical tests (Wilson's and McMurray's), MSK-US and MRI-based ICRS grading may support clinical orientation and preoperative risk stratification, forming a pragmatic diagnostic framework rather than a definitive staging tool.

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Publication Details

Journal
Life
Published
2026-01-05
DOI
https://doi.org/10.3390/life16010080
Primary Topic
Musculoskeletal synovial abnormalities and treatments
Type
article
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article

A Multimodal Diagnostic Algorithm for Focal Knee Chondral Defects: Correlating Clinical Tests, Musculoskeletal Ultrasound, and MRI-Based ICRS Grading

Robert Gherghel, Paul Dan Sîrbu, Elena Rezuş, Daniel Mădălin Coja et al.
Life
Musculoskeletal synovial abnormalities and treatments
article

A Multimodal Diagnostic Algorithm for Focal Knee Chondral Defects: Correlating Clinical Tests, Musculoskeletal Ultrasound, and MRI-Based ICRS Grading

Robert Gherghel, Paul Dan Sîrbu, Elena Rezuş, Daniel Mădălin Coja, Sonia Gabriela Neagu, Carmina Liana Mușat, Ilie Onu, Corneliu Mircea Codreanu, Daniel Andrei Iordan, Georgiana Bianca Constantin
article en

Abstract

Symptom severity alone does not reliably distinguish between ICRS Grade 3 and Grade 4 focal chondral lesions. McMurray's test, while not cartilage-specific, was associated with lesion complexity due to its reflection of concomitant meniscal pathology rather than cartilage depth itself. Accordingly, McMurray's test should be interpreted as an indirect clinical indicator of combined osteochondral-meniscal involvement. The integration of targeted clinical tests (Wilson's and McMurray's), MSK-US and MRI-based ICRS grading may support clinical orientation and preoperative risk stratification, forming a pragmatic diagnostic framework rather than a definitive staging tool.

LifeVol. 16(1)
Lucian Blaga University of Sibiu (RO), Grigore T. Popa University of Medicine and Pharmacy (RO), "Dunarea de Jos" University of Galati (RO), Microelectronica (Romania) (RO)
Reduced inequalities
Openalex Percentile: Top 98%
Musculoskeletal synovial abnormalities and treatments
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A Multimodal Diagnostic Algorithm for Focal Knee Chondral Defects: Correlating Clinical Tests, Musculoskeletal Ultrasound, and MRI-Based ICRS Grading — Robert Gherghel, Paul Dan Sîrbu, et al. · Life (2026) | TGRS Research Map | TGRS