Integration of chromosomal microarray analysis and whole-exome sequencing for prenatal diagnosis of fetuses with cardiac ultrasound anomalies
This study highlights the clinical significance of CMA and WES in the prenatal diagnosis of genetic disorders in fetuses presenting with cardiac ultrasound abnormalities. It affirms the robust utility of CMA and WES methodologies in prenatal diagnosis and genetic counseling.
Authors
- Yan Wu (ORCID: https://orcid.org/0000-0002-2847-9418)
- Ji Yuan
- Yawen Qiang
- Gui Mei Chen
- Weisheng Cheng
- Renhua Wu (ORCID: https://orcid.org/0000-0002-7070-9707)
- Fang Yang
- Xiang Liu
- Fang Liu
Institutions
- Anhui University of Science and Technology (CN)
- Anhui Medical University (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- Frontiers in Genetics
- Published
- 2026-01-04
- DOI
- https://doi.org/10.3389/fgene.2025.1668252
- Primary Topic
- Prenatal Screening and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- Natural Science Foundation of Anhui Province
- National Key Research and Development Program of China