Dominant TET2 mutations predict adverse prognosis in cytogenetically normal acute myeloid leukemia patients
The prognostic impact of <i>TET2</i> mutations is not determined by VAF, but rather by <i>TET2</i> clonal dominance and the interplay between mutations within the same clone.
Authors
- S S Li
- H W Wang
- Hongwei Wang
- X. Chen
- Yi Zhang
- Jingyi Feng
- Miao Zhang (ORCID: https://orcid.org/0000-0001-5490-1283)
- Sicheng Bian
- Zhuanghui Hao
- Xufeng Huang
- Jingjing Xia
- Jianmei Chang
- Wanfang Yang
- Fanggang Ren
- Miaoke Song
Institutions
- University of Debrecen (HU)
- Shanxi Medical University (CN)
- Jinzhong University (CN)
- Second Hospital of Shanxi Medical University (CN)
- MetroHealth Medical Center (US)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2026-01-05
- DOI
- https://doi.org/10.3389/fonc.2025.1730830
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00