CMsiRNAdb: a database of chemically modified SiRNA silencing efficiency for nucleic acid drug design

CMsiRNAdb provides critical data support and analytical tools for the rational design and rapid optimization of siRNA drugs. By standardizing data and offering predictive capabilities, it significantly advances the development of nucleic acid therapeutics.

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Publication Details

Journal
BMC Bioinformatics
Published
2026-01-03
DOI
https://doi.org/10.1186/s12859-025-06359-y
Primary Topic
RNA Interference and Gene Delivery
Type
article
Field-Weighted Citation Impact
0.00
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article

CMsiRNAdb: a database of chemically modified SiRNA silencing efficiency for nucleic acid drug design

Y. H. Zhang, C. Chen, Yufan Yang, Juan Feng et al.
BMC Bioinformatics
RNA Interference and Gene Delivery
article

CMsiRNAdb: a database of chemically modified SiRNA silencing efficiency for nucleic acid drug design

Y. H. Zhang, C. Chen, Yufan Yang, Juan Feng, Kejun Deng, Hasan Zulfiqar, Sicheng He, Gaogao Xue, Xianrun Pan
article en

Abstract

CMsiRNAdb provides critical data support and analytical tools for the rational design and rapid optimization of siRNA drugs. By standardizing data and offering predictive capabilities, it significantly advances the development of nucleic acid therapeutics.

BMC BioinformaticsVol. 27(1)
University of Electronic Science and Technology of China (CN), Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Suzhou Institute of Systems Medicine (CN), Sichuan Academy of Traditional Chinese Medicine (CN), Chengdu University of Traditional Chinese Medicine (CN)
Openalex Percentile: Top 98%
RNA Interference and Gene Delivery
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CMsiRNAdb: a database of chemically modified SiRNA silencing efficiency for nucleic acid drug design — Y. H. Zhang, C. Chen, et al. · BMC Bioinformatics (2026) | TGRS Research Map | TGRS