TNA in Dermatology: Throughput, Incoherence, and Skin Health

Dermatology traditionally models skin health through barrier function, immune responses, and microbiome balance. This paper proposes a TNA-based framework, viewing skin as an open system where epidermal and dermal coherence requires continuous throughput (Ψ) to discharge incoming incoherence (G). When G exceeds Ψ, accumulated incoherence (ℵ) manifests as dermatitis, acne, psoriasis, or delayed wound healing. Environmental factors, aging, and lifestyle are reframed as throughput stressors rather than primary defects. The model is falsifiable, predictive, and integrates barrier, immune, and microbiome dynamics in a unified framework.

Authors

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-01-03
DOI
https://doi.org/10.5281/zenodo.18141041
Primary Topic
Dermatology and Skin Diseases
Type
article
Field-Weighted Citation Impact
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article

TNA in Dermatology: Throughput, Incoherence, and Skin Health

Claudio Bresciano
Zenodo (CERN European Organization for Nuclear Research)
Dermatology and Skin Diseases
article

TNA in Dermatology: Throughput, Incoherence, and Skin Health

Claudio Bresciano
article en

Abstract

Dermatology traditionally models skin health through barrier function, immune responses, and microbiome balance. This paper proposes a TNA-based framework, viewing skin as an open system where epidermal and dermal coherence requires continuous throughput (Ψ) to discharge incoming incoherence (G). When G exceeds Ψ, accumulated incoherence (ℵ) manifests as dermatitis, acne, psoriasis, or delayed wound healing. Environmental factors, aging, and lifestyle are reframed as throughput stressors rather than primary defects. The model is falsifiable, predictive, and integrates barrier, immune, and microbiome dynamics in a unified framework.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 98%
Dermatology and Skin Diseases
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TNA in Dermatology: Throughput, Incoherence, and Skin Health — Claudio Bresciano · Zenodo (CERN European Organization for Nuclear Research) (2026) | TGRS Research Map | TGRS