D-ribose-loaded hydrogel modulates necrosis progression and wound stability in a rabbit random-pattern skin flap model
Local delivery of a D-ribose-loaded hydrogel modulated necrosis progression and improved wound stability in a rabbit random-pattern skin flap model. These findings support metabolically active hydrogel-based strategies as a promising adjunct to enhance flap reliability under ischemic conditions.
Authors
- Khalil Rostami
- Omid Zehtab
- Parisa Haghi (ORCID: https://orcid.org/0000-0003-2290-1929)
- Helia Ghorbani
- Seyed Esmaeil Tabatabaei
- Payam Asadi Ghahnaviyeh
- Mahdi Mohebbi
Institutions
- Zanjan University of Medical Sciences (IR)
- Shahid Beheshti University of Medical Sciences (IR)
- Tehran University of Medical Sciences (IR)
Publication Details
- Journal
- JPRAS Open
- Published
- 2026-01-03
- DOI
- https://doi.org/10.1016/j.jpra.2025.12.033
- Primary Topic
- Wound Healing and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00