Impact of dose and compliance of antidementia medications on long-term outcomes in Alzheimer’s disease: a nationwide real-world study
Both medication dosage and persistence were independently associated with better long-term outcomes in AD. Maintaining optimal treatment during the early disease period may delay disease progression and improve survival within five years. This nationwide real-world study provides robust evidence supporting the importance of sustained, adequate antidementia therapy in clinical practice.
Authors
- Si Baek Lee (ORCID: https://orcid.org/0000-0002-7455-1943)
- Eunbuel Ko
- Jeong Wook Park (ORCID: https://orcid.org/0000-0002-3990-4715)
- Yoonjong Bae
- Seong Hoon Kim
- Yun Jeong Hong
- Mina Kim
- Taewon Kim
- Myung Ah Lee
- Dong Won Yang
Institutions
- Hanmi Pharmaceutical (South Korea) (KR)
- The Catholic University of Korea Incheon St. Mary's Hospital (KR)
- The Catholic University of Korea Uijeongbu St. Mary's Hospital (KR)
- The Catholic University of Korea Seoul St. Mary's Hospital (KR)
- Catholic University of Korea (KR)
Publication Details
- Journal
- Alzheimer s Research & Therapy
- Published
- 2026-01-03
- DOI
- https://doi.org/10.1186/s13195-025-01942-0
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00