Investigating the anticancer potential of boric acid against human gastric adenocarcinoma cells

Gastric cancer is a major contributor to cancer-related mortality worldwide, and the search for effective, targeted, and biocompatible therapeutic agents remains ongoing. Boric acid, a biologically active and low toxicity boron compound, has recently gained attention for its potential anticancer properties. This study aimed to investigate cytotoxic and proapoptotic effects of boric acid on human gastric adenocarcinoma cells (AGS) in vitro. The cell viability was assessed using a cytotoxicity assay following 24 h boric acid treatment, the IC50 value for AGS cells can be confidently stated as