Negative impact of medical ozone therapy on femur fracture healing in a rat model
Medical ozone therapy demonstrated a detrimental effect on fracture union, as evidenced by inferior radiological, histopathological, immunohistochemical, histochemical, and biomechanical outcomes. These findings indicate that systemic ozone treatment may adversely influence bone healing processes.
Authors
- Turan Cihan Dülgeroğlu (ORCID: https://orcid.org/0000-0002-9661-5418)
- Nihat Demirhan Demirkıran (ORCID: https://orcid.org/0000-0002-0724-9672)
- Sabit Numan Kuyubaşı
- Sermet İnal
- Süleyman Kaan Öner
- Ayşe Nur Değer
- Süleyman Kozlu
Institutions
- Izmir University (TR)
- University of Health Science (KH)
- Kütahya Dumlupınar Üniversitesi (TR)
- Kutahya Saglik Bilimleri Universitesi
Publication Details
- Journal
- Journal of Orthopaedic Surgery and Research
- Published
- 2026-01-04
- DOI
- https://doi.org/10.1186/s13018-025-06622-1
- Primary Topic
- Medical and Biological Ozone Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00