INTEGRATED EXPRESSION PROFILE OF THE MMP–TIMP–MIRNA AXIS IN BREAST CANCER CELL LINES OF DIFFERENT MOLECULAR SUBTYPES

The study demonstrates that the MMP-TIMP-miRNA axis exhibits subtype-specific expression patterns in the BC cell lines. The observed heterogeneity highlights the importance of post-transcriptional regulation and suggests that integrated profiling of MMPs, TIMPs, and regulatory miRNAs may provide novel insights into the invasive potential of BC and identify candidate biomarkers for clinical validation.