Application of deep learning technology in breast cancer: a systematic review of segmentation, detection, and classification approaches

Deep learning offers considerable promise to support early detection, risk stratification and workflow efficiency across breast imaging modalities, with CNNs and Transformers providing complementary strengths for local fine-detail versus global contextual modelling. Nevertheless, the current evidence base is constrained by heterogeneous designs, limited reporting of study quality and biased datasets, so reported performance should not be interpreted as definitive proof of clinical readiness. Future research should prioritise multi-centre, demographically diverse cohorts, transparent quality assessment, external and prospective validation, and evaluation of reader and workflow impact. Developing explainable, fairness-aware and privacy-preserving systems-such as those enabled by interpretable architectures and federated learning-will be essential for safe and equitable translation of deep learning tools into routine breast cancer care.

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Publication Details

Journal
BioMedical Engineering OnLine
Published
2026-01-04
DOI
https://doi.org/10.1186/s12938-025-01502-5
Citations
2
Primary Topic
AI in cancer detection
Type
article
Field-Weighted Citation Impact
104.19
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article

Application of deep learning technology in breast cancer: a systematic review of segmentation, detection, and classification approaches

Jia Liu, Ke Zhang, Yafei Miao, Linqian Li et al.
2 citations
BioMedical Engineering OnLine
AI in cancer detection
104.19
article

Application of deep learning technology in breast cancer: a systematic review of segmentation, detection, and classification approaches

Jia Liu, Ke Zhang, Yafei Miao, Linqian Li, Qianqian Han, Jianguo Wu, Di Yang, Shuo Gao, Xu Zhang, Yasong Shi
article en
2 citations

Abstract

Deep learning offers considerable promise to support early detection, risk stratification and workflow efficiency across breast imaging modalities, with CNNs and Transformers providing complementary strengths for local fine-detail versus global contextual modelling. Nevertheless, the current evidence base is constrained by heterogeneous designs, limited reporting of study quality and biased datasets, so reported performance should not be interpreted as definitive proof of clinical readiness. Future research should prioritise multi-centre, demographically diverse cohorts, transparent quality assessment, external and prospective validation, and evaluation of reader and workflow impact. Developing explainable, fairness-aware and privacy-preserving systems-such as those enabled by interpretable architectures and federated learning-will be essential for safe and equitable translation of deep learning tools into routine breast cancer care.

BioMedical Engineering OnLineVol. 25(1)
Affiliated Hospital of Hebei University (CN), Hebei University (CN)
Openalex Percentile: Top 0%
AI in cancer detection
104.19
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