CYTOSTATIC EFFECTS AND MECHANISMS OF ACTION OF BACTERIAL LECTIN OF BACILLUS SUBTILIS IMV B-7724 ON BREAST CANCER CELL LINES OF DIFFERENT MOLECULAR SUBTYPES

Lectin of B. subtilis IMV B-7724 exerts multifaceted effects on BC cells of different molecular subtypes, including the suppression of cell proliferation, activation of apoptosis, and cell cycle modulation. The observed differences between the BC cell lines suggest that the lectin efficacy depends on both the molecular profile of the cells and the mode of apoptosis regulation (p53-dependent or p53-independent), warranting further studies to identify key targets.