Efficacy and safety of sequential versus concurrent administration of immune checkpoint inhibitors with radiotherapy in solid tumors: a systematic review and network meta-analysis
Compared with concurrent administration of ICI with RT, sequential administration of ICI after RT improves survival outcomes without increasing toxicity. Further studies are needed to define the optimal timing of RT and ICIs to maximize efficacy while minimizing AEs.
Authors
- E. Edmund Kim (ORCID: https://orcid.org/0000-0001-9078-4934)
- Sieun Lee (ORCID: https://orcid.org/0009-0006-1858-574X)
- Doran Kim
- Hye Kyung Jin (ORCID: https://orcid.org/0000-0002-2106-1086)
- Jiwon Baek (ORCID: https://orcid.org/0009-0002-7708-8779)
Institutions
- Chung-Ang University (KR)
Publication Details
- Journal
- Cancer Immunology Immunotherapy
- Published
- 2026-01-03
- DOI
- https://doi.org/10.1007/s00262-025-04277-9
- Citations
- 1
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 24.20