Comparative performance of radiomics models based on 3D-FLAIR-CUBE and MPRAGE sequences gadolinium-induced labyrinth MRI protocols for predicting endolymphatic hydrops in Ménière’s disease

This study developed the first radiomics model based on gadolinium-induced labyrinth MRI using 3D-FLAIR-CUBE and 3D-MPRAGE sequences. The MLP model based on 3D-FLAIR-CUBE demonstrated the best diagnostic performance. Focusing on vestibular imaging features can improve the detection of endolymphatic hydrops. This tool may assist in guiding personalized treatment decisions, particularly for patients with refractory Ménière's disease.