Evolution of pneumococcal serotypes, vaccination uptake, and prognosis of invasive pneumococcal disease: A 9-year multicentre cohort study in Granada (Andalusia, Spain)

Low frequency of pneumococcal vaccination uptake in adult patients with IPD was demonstrated. Older age, living in long-term care facilities, dependency, septic shock at admission, and no previous pneumococcal vaccination were associated with higher in-hospital mortality. Immunization strategies should imperatively be optimised so as to reduce mortality from IPD.