Norepinephrine and dopamine Imbalance in the medial frontal gyrus from patients with Alzheimer's disease

By revealing a selective increase in NE turnover and DA levels in the medial frontal lobe, these data may help to clarify the neurochemical imbalance linking cortical to subcortical neurodegeneration, such as that of the locus coeruleus and ventral tegmental area, to catecholamine innervation of the frontal cortex.

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Publication Details

Journal
IBRO Neuroscience Reports
Published
2026-01-03
DOI
https://doi.org/10.1016/j.ibneur.2026.01.001
Primary Topic
Neurotransmitter Receptor Influence on Behavior
Type
article
Field-Weighted Citation Impact
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article

Norepinephrine and dopamine Imbalance in the medial frontal gyrus from patients with Alzheimer's disease

Giovanni Augusto Carlesimo, Emanuele Claudio Latagliata, Bernard Hanseeuw, Yasmine Salman et al.
IBRO Neuroscience Reports
Neurotransmitter Receptor Influence on Behavior
article

Norepinephrine and dopamine Imbalance in the medial frontal gyrus from patients with Alzheimer's disease

Giovanni Augusto Carlesimo, Emanuele Claudio Latagliata, Bernard Hanseeuw, Yasmine Salman, Michela Fratini, Silvia Capuani, Charles Nicaise, Roberto Coccurello, Zuleyha Nihan Yurtsever
article en

Abstract

By revealing a selective increase in NE turnover and DA levels in the medial frontal lobe, these data may help to clarify the neurochemical imbalance linking cortical to subcortical neurodegeneration, such as that of the locus coeruleus and ventral tegmental area, to catecholamine innervation of the frontal cortex.

IBRO Neuroscience ReportsVol. 20
University of Rome Tor Vergata (IT), Uninett (Norway) (NO), Cliniques Universitaires Saint-Luc (BE), University of Namur (BE), Institute for Complex Systems (IT), Fondazione Santa Lucia (IT), Sapienza University of Rome (IT)
Openalex Percentile: Top 97%
Neurotransmitter Receptor Influence on Behavior
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