Prevalence and clinical risk factors for methotrexate intolerance in patients with juvenile idiopathic arthritis.

MTX intolerance is relatively common in pediatric patients with JIA and is associated with older age at disease onset and MTX initiation, as well as the use of MTX as first-line therapy.

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Journal
PubMed
Published
2026-01-02
Primary Topic
Autoimmune and Inflammatory Disorders Research
Type
article
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article

Prevalence and clinical risk factors for methotrexate intolerance in patients with juvenile idiopathic arthritis.

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PubMed
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Prevalence and clinical risk factors for methotrexate intolerance in patients with juvenile idiopathic arthritis.

Dragana Lazarević, Predrag Ostojić, Maja Bijelic, Gordana Sušić, Goran Radunović, Dušica Novaković, Tijana Dimkić-Tomić, Nataša Mujović, Andjela Dimkic-Milenkovic, Stefan Antonije Djordjevic, Smiljka Kovacevic, Hristina Petrovic, Vladimir Milenkovic
article en

Abstract

MTX intolerance is relatively common in pediatric patients with JIA and is associated with older age at disease onset and MTX initiation, as well as the use of MTX as first-line therapy.

PubMedVol. 4(4)
Uniwersytecki Szpital Dziecięcy (PL), Institute of Rheumatology (CZ), Children's Clinical University Hospital (LV)
Good health and well-being
Openalex Percentile: Top 98%
Autoimmune and Inflammatory Disorders Research
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