Rat Bite Fever: It’s Still a Threat

<i>Streptobacillus moniliformis</i> is considered normal flora of the upper respiratory tract of rodents and is the predominant cause of rat bite fever in North America. Although patients with rat bite fever oftentimes present with migratory polyarthralgia, cultures of affected joints do not grow bacteria in the vast majority of cases. We present a case of a 32-year-old woman who initially presented with a painful, swollen right index finger proximal interphalangeal (PIP) joint following a bite from her pet rat. After initial treatment with empiric antibiotics did not clear the infection, PIP joint irrigation and debridement revealed culture-positive septic arthritis. This case illustrates the patient's unusual presentation of <i>S</i>. <i>moniliformis</i> infection through septic arthritis of the PIP joint.

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Publication Details

Journal
Journal of Hand Surgery Global Online
Published
2026-01-02
DOI
https://doi.org/10.1016/j.jhsg.2025.100901
Primary Topic
Rabies epidemiology and control
Type
article
Field-Weighted Citation Impact
0.00
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article

Rat Bite Fever: It’s Still a Threat

Robert E. Van Demark, Matthew Anderson, Kyler A. Hardie, Alexander J. Bergeson
Journal of Hand Surgery Global Online
Rabies epidemiology and control
article

Rat Bite Fever: It’s Still a Threat

Robert E. Van Demark, Matthew Anderson, Kyler A. Hardie, Alexander J. Bergeson
article en

Abstract

<i>Streptobacillus moniliformis</i> is considered normal flora of the upper respiratory tract of rodents and is the predominant cause of rat bite fever in North America. Although patients with rat bite fever oftentimes present with migratory polyarthralgia, cultures of affected joints do not grow bacteria in the vast majority of cases. We present a case of a 32-year-old woman who initially presented with a painful, swollen right index finger proximal interphalangeal (PIP) joint following a bite from her pet rat. After initial treatment with empiric antibiotics did not clear the infection, PIP joint irrigation and debridement revealed culture-positive septic arthritis. This case illustrates the patient's unusual presentation of <i>S</i>. <i>moniliformis</i> infection through septic arthritis of the PIP joint.

Journal of Hand Surgery Global OnlineVol. 8(2)
University of South Dakota (US), University of North Dakota (US)
Openalex Percentile: Top 98%
Rabies epidemiology and control
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