Immediate Brainstem Hemorrhage after Thrombolysis in Ischemic Stroke With Poorly Controlled Hypertension: Insights From Three Clinical Cases

These cases suggest that fatal brainstem hemorrhage may occur after TNK thrombolysis in minor stroke. For patients with a history of poorly controlled hypertension, careful risk assessment and aggressive blood pressure management are critical if thrombolysis is considered.

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Publication Details

Journal
Journal of Central Nervous System Disease
Published
2026-01-02
DOI
https://doi.org/10.1177/11795735251409050
Primary Topic
Acute Ischemic Stroke Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Immediate Brainstem Hemorrhage after Thrombolysis in Ischemic Stroke With Poorly Controlled Hypertension: Insights From Three Clinical Cases

Li Shen, Bin Mei, Nao Yan, Dong Sun et al.
Journal of Central Nervous System Disease
Acute Ischemic Stroke Management
article

Immediate Brainstem Hemorrhage after Thrombolysis in Ischemic Stroke With Poorly Controlled Hypertension: Insights From Three Clinical Cases

Li Shen, Bin Mei, Nao Yan, Dong Sun, Niao Yang
article en

Abstract

These cases suggest that fatal brainstem hemorrhage may occur after TNK thrombolysis in minor stroke. For patients with a history of poorly controlled hypertension, careful risk assessment and aggressive blood pressure management are critical if thrombolysis is considered.

Journal of Central Nervous System DiseaseVol. 18
Wuhan University (CN), Zhongnan Hospital of Wuhan University (CN), Wuhan University of Science and Technology (CN)
Good health and well-being
Openalex Percentile: Top 98%
Acute Ischemic Stroke Management
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