Real-world outcomes of ustekinumab, vedolizumab, and tumor necrosis factor inhibitors in very-early-onset inflammatory bowel disease: a multi-center cohort study

UST and VDZ were effective and well tolerated even when used as second-line or subsequent therapies for VEO-IBD.

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Publication Details

Journal
Journal of Gastroenterology
Published
2026-01-03
DOI
https://doi.org/10.1007/s00535-025-02334-9
Primary Topic
Inflammatory Bowel Disease
Type
article
Field-Weighted Citation Impact
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article

Real-world outcomes of ustekinumab, vedolizumab, and tumor necrosis factor inhibitors in very-early-onset inflammatory bowel disease: a multi-center cohort study

Naoya Tsumura, Yugo Takaki, Yuri Etani, Ryo Ebana et al.
Journal of Gastroenterology
Inflammatory Bowel Disease
article

Real-world outcomes of ustekinumab, vedolizumab, and tumor necrosis factor inhibitors in very-early-onset inflammatory bowel disease: a multi-center cohort study

Naoya Tsumura, Yugo Takaki, Yuri Etani, Ryo Ebana, M Usami, T Ishige, Ryusuke Nambu, Hiroki Fujikawa, Shingo Kurasawa, Tatsuki Mizuochi, Koji Yokoyama, Yusuke Hoshi, Itaru Iwama, Fumihiko Kakuta, Emiri Kaji, M. Masashi Yoshida, Shin-ichiro Hagiwara, Ichiro Takeuchi, Takahiro Kudo, Atsushi Yoden, Katsuhiro Arai, Takuya Nishizawa, Hirotaka Shimizu, Hideki Kumagai
article en

Abstract

UST and VDZ were effective and well tolerated even when used as second-line or subsequent therapies for VEO-IBD.

Journal of Gastroenterology
Kanazawa University (JP), Kurume University (JP), Hiroshima University (JP), Shinshu University (JP), Jichi Medical University (JP), Kanazawa Medical University (JP), Gunma University (JP), Juntendo University (JP), Miyagi Children's Hospital (JP), Osaka Women's and Children's Hospital (JP), Saitama Children's Medical Center (JP), Japanese Red Cross Kumamoto Hospital (JP), Okinawa Prefectural Chubu Hospital (JP), National Center For Child Health and Development (JP), Toyo Institute of Food Technology (JP), Osaka University of Pharmaceutical Sciences (JP)
Good health and well-being
Openalex Percentile: Top 97%
Inflammatory Bowel Disease
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