Mechanisms by Which miR-584-5p Regulates Osteogenic Differentiation and Inflammation in Human Dental Pulp Stem Cells
miR-584-5p was highly expressed in pulpitis and exerted dual regulatory effects on hDPSCs by inhibiting their osteogenic differentiation and promoting their inflammatory response, through direct targeting and suppression of PTEN.
Authors
- Yan Zou
- Huiling Qin (ORCID: https://orcid.org/0009-0005-5287-0192)
- Jing Dong
- Fenglin Chen
Institutions
- Guangdong Medical College (CN)
- Second Affiliated Hospital of Guangzhou Medical University (CN)
- Lianyungang Oriental Hospital (CN)
- Shanghai Ninth People's Hospital (CN)
- Affiliated Hospital of Youjiang Medical University for Nationalities (CN)
- Jiangsu Provincial Hospital of Traditional Chinese Medicine (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- International Dental Journal
- Published
- 2026-01-03
- DOI
- https://doi.org/10.1016/j.identj.2025.109356
- Primary Topic
- Bone Metabolism and Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00