Comprehensive profiling of lactylation-associated genes in pulmonary hypertension through bulk and single-cell RNA sequencing integration

We analyzed lactylation-related genes in PH, identifying LCP1 as a key diagnostic marker, and described immune cell lactylation in PH patients, offering insights for future research.

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Publication Details

Journal
Respiratory Research
Published
2026-01-03
DOI
https://doi.org/10.1186/s12931-025-03446-9
Citations
1
Primary Topic
Pulmonary Hypertension Research and Treatments
Type
article
Field-Weighted Citation Impact
36.44
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article

Comprehensive profiling of lactylation-associated genes in pulmonary hypertension through bulk and single-cell RNA sequencing integration

Wenlong Wu, Xuejin Lu, Wenhao Li, Ying Wang et al.
1 citations
Respiratory Research
Pulmonary Hypertension Research and Treatments
36.44
article

Comprehensive profiling of lactylation-associated genes in pulmonary hypertension through bulk and single-cell RNA sequencing integration

Wenlong Wu, Xuejin Lu, Wenhao Li, Ying Wang, Ran Wang, Wanrong Wang, Rui Han, Daxiong Zeng
article en
1 citations

Abstract

We analyzed lactylation-related genes in PH, identifying LCP1 as a key diagnostic marker, and described immune cell lactylation in PH patients, offering insights for future research.

Respiratory ResearchVol. 27(1)
Anhui Medical University (CN), Soochow University (CN), Second Affiliated Hospital of Soochow University (CN), First Affiliated Hospital of Anhui Medical University (CN), Second Affiliated Hospital of Anhui Medical University (CN), First Affiliated Hospital of Soochow University (CN), Third People's Hospital of Hefei (CN), Hefei Infectious Disease Hospital (CN)
Openalex Percentile: Top 2%
Pulmonary Hypertension Research and Treatments
36.44
DOIOpen Access PDFOpenAlex
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Comprehensive profiling of lactylation-associated genes in pulmonary hypertension through bulk and single-cell RNA sequencing integration — Wenlong Wu, Xuejin Lu, et al. · Respiratory Research (2026) | TGRS Research Map | TGRS