Quantification of bone microarchitecture and strength with photon-counting detector CT at different radiation doses: an ex-vivo and in-vivo comparison with HR-pQCT

PCD-CT strongly correlated with HR-pQCT in trabecular microarchitecture measurements at the distal radius and tibia at low, clinically acceptable, radiation dose. Between-modality differences in microarchitecture values are likely related to chosen image analysis settings.

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Publication Details

Journal
European Journal of Radiology
Published
2026-01-03
DOI
https://doi.org/10.1016/j.ejrad.2025.112630
Primary Topic
Advanced X-ray and CT Imaging
Type
article
Field-Weighted Citation Impact
0.00

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article

Quantification of bone microarchitecture and strength with photon-counting detector CT at different radiation doses: an ex-vivo and in-vivo comparison with HR-pQCT

Edwin H. G. Oei, Joop P. van den Bergh, Sofia Spinthaki, Melissa S. A. M. Bevers et al.
European Journal of Radiology
Advanced X-ray and CT Imaging
article

Quantification of bone microarchitecture and strength with photon-counting detector CT at different radiation doses: an ex-vivo and in-vivo comparison with HR-pQCT

Edwin H. G. Oei, Joop P. van den Bergh, Sofia Spinthaki, Melissa S. A. M. Bevers, Joeri Kok, Bert van Rietbergen, Ronald Booij
article en

Abstract

PCD-CT strongly correlated with HR-pQCT in trabecular microarchitecture measurements at the distal radius and tibia at low, clinically acceptable, radiation dose. Between-modality differences in microarchitecture values are likely related to chosen image analysis settings.

European Journal of RadiologyVol. 196
Maastricht University Medical Centre (NL), Erasmus MC (NL), Maastricht University (NL), Eindhoven University of Technology (NL), Erasmus University Rotterdam (NL)
European Commission, Erasmus Medisch Centrum, Vlaamse regering, Interreg Vlaanderen-Nederland, European Regional Development Fund, Interreg
Openalex Percentile: Top 98%
Advanced X-ray and CT Imaging
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