Population estimates, trends, characteristics and prognostic outcomes of cardiovascular-kidney-liver-metabolic health: A population-based study

The CKLM multimorbidity burden is rising in the US population. Higher CKLM burden (≥3 CKLM diseases) and CKD-centric phenotypes (MASLD-T2D-CKD or T2D-CKD) independently predict the highest mortality risk.

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Publication Details

Journal
American Journal of Preventive Cardiology
Published
2026-01-03
DOI
https://doi.org/10.1016/j.ajpc.2025.101405
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Population estimates, trends, characteristics and prognostic outcomes of cardiovascular-kidney-liver-metabolic health: A population-based study

Srinithy Nagarajan, Martin Tze Wah Kueh, Mark Y. Chan, Anurag Mehta et al.
American Journal of Preventive Cardiology
Liver Disease Diagnosis and Treatment
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Population estimates, trends, characteristics and prognostic outcomes of cardiovascular-kidney-liver-metabolic health: A population-based study

Srinithy Nagarajan, Martin Tze Wah Kueh, Mark Y. Chan, Anurag Mehta, Haryo Raden Himan, Rachel Goh, Mamas A Mamas, Xin Zhou, Jiong Wei Wang, Yip Han Chin, Nicholas WS Chew, Bryan Chong, Mark M Muthiah, Yalkin Yazicioglu, Yiming Chen, Muhammad Ali Zaib Khan
article en

Abstract

The CKLM multimorbidity burden is rising in the US population. Higher CKLM burden (≥3 CKLM diseases) and CKD-centric phenotypes (MASLD-T2D-CKD or T2D-CKD) independently predict the highest mortality risk.

American Journal of Preventive CardiologyVol. 25
University College Dublin (IE), RCSI & UCD Malaysia Campus (MY), Royal College of Surgeons in Ireland (IE), Emory University (US), National University of Singapore (SG), Baylor College of Medicine (US), Tianjin Medical University General Hospital (CN), Emory Clinic (US), National University Heart Centre Singapore (SG), Heart Hospital Baylor Plano (US), National University Hospital (SG), National University Health System (SG), Baylor Scott & White Health (US), Keele University (GB)
Good health and well-being
Openalex Percentile: Top 98%
Liver Disease Diagnosis and Treatment
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