A model for predicting the likelihood of negative culture results in children with osteoarticular infections
CRP was identified as a key predictor of negative blood culture results. The presence of septic arthritis, neutrophil percentage, and CRP was identified as a key predictor of negative pus culture results. The nomogram constructed with pus culture predictors had good discrimination and clinical applicability and has potential for the early identification of culture-negative OAI cases in the clinic. This tool could optimize etiological investigation strategies and improve the efficiency of clinical diagnosis.
Authors
- Gianfilippo Caggiari (ORCID: https://orcid.org/0000-0002-7618-6732)
- Xin Qiu (ORCID: https://orcid.org/0000-0003-2320-7963)
- Haoran Feng (ORCID: https://orcid.org/0009-0001-0239-9137)
- Jiahui Li
- Zilong Huang
- Huifeng Yang
- Guibing Fu
- Zhongjian Xie
- Gen Liu
- Ruitao Lu
- Jianlin Chen
- Hansheng Deng
Institutions
- University of Sassari (IT)
- Shantou University (CN)
- Shantou University Medical College (CN)
- Shenzhen Institute for Drug Control (CN)
- Shenzhen Children's Hospital (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2026-01-02
- DOI
- https://doi.org/10.1186/s40001-025-03773-z
- Primary Topic
- Orthopedic Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00