Impact of interaction between interleukin-27 gene polymorphisms and smoking with susceptibility to non-small cell lung cancer in Chinese Han population
Our results support an important association of the IL- 27 gene rs153109, rs181206, smoking and alcohol consumption with increased NSCLC risk. We also found a significant impact of an interaction between rs153109 minor allele and ever or current smoking on NSCLC risk.
Authors
- Feng Ni
- Yun Guan
- Jiamin Zhu (ORCID: https://orcid.org/0000-0001-9906-9849)
- Jing Y Cai
- Cheng Tan
- Xiaogang Zhai
- Baixia Yang
Institutions
- Nantong University (CN)
- Affiliated Hospital of Nantong University (CN)
- Jiangyin People's Hospital (CN)
- Nantong Tumor Hospital (CN)
Publication Details
- Journal
- World Journal of Surgical Oncology
- Published
- 2026-01-02
- DOI
- https://doi.org/10.1186/s12957-025-04078-5
- Primary Topic
- Psoriasis: Treatment and Pathogenesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00