Genome-Wide Association Study for Glucocorticoid-Induced Ocular Hypertension
We have identified genome-wide significant common variants associated with GC-IOP change, as well as genes and rare variants that may influence GC-induced IOP change.
Authors
- George N. Papaliodis (ORCID: https://orcid.org/0000-0002-5029-5316)
- Janine Yang (ORCID: https://orcid.org/0000-0003-1324-7590)
- Alicia Huerta‐Chagoya (ORCID: https://orcid.org/0000-0001-6218-3904)
- Ashley Li (ORCID: https://orcid.org/0009-0008-3394-010X)
- H. Wafapoor
- Renee Liu (ORCID: https://orcid.org/0000-0003-4576-6918)
- Ayellet V. Segrè (ORCID: https://orcid.org/0000-0001-6806-5845)
- Lucy Q. Shen (ORCID: https://orcid.org/0000-0002-0360-1296)
- Y. Zhao
- Elizabeth J. Rossin (ORCID: https://orcid.org/0000-0002-0052-9575)
- Katie Huynh
- Lynn K. Stanwyck (ORCID: https://orcid.org/0000-0001-5140-3246)
- D. N. Sang
- Gayatri Susarla
- Alexander M. Eaton (ORCID: https://orcid.org/0000-0002-5044-3358)
- Da Meng
- Liyin Chen
- Weilin Chan (ORCID: https://orcid.org/0000-0003-1417-9606)
- Samuel Han (ORCID: https://orcid.org/0000-0003-4695-2720)
- Ananya Mukundan
- Jyoti Lama
- Antonio Cutino
- Irma Benavides
- Janey J Wiggs
- Lucia Sobrin
- Christine Elkins
Institutions
- Broad Institute (US)
- Massachusetts Eye and Ear Infirmary (US)
- Harvard University (US)
- New England Institute of Art (US)
- Massachusetts General Hospital (US)
- Alimera Sciences (United States) (US)
- Retina Health Center (US)
Publication Details
- Journal
- medRxiv
- Published
- 2026-01-02
- DOI
- https://doi.org/10.64898/2025.12.31.25343232
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Research to Prevent Blindness
- Glaucoma Foundation
- Sanofi
- Massachusetts Lions Eye Research Fund
- Alimera Sciences
- National Institutes of Health
- National Human Genome Research Institute
- National Eye Institute