Effect of Sphingosine-1-Phosphate Receptor Modulators on Insulin Resistance: A Review
S1PR modulators are effective disease-modifying therapies in multiple sclerosis, but emerging evidence suggests a possible impact on insulin signaling and glucose metabolism. Vigilance in metabolic monitoring is recommended, particularly in patients with diabetes or other risk factors for insulin resistance.
Authors
- Arturo Figueroa (ORCID: https://orcid.org/0000-0001-9710-038X)
- Ana Rodríguez Regal
- Sarah Lopez (ORCID: https://orcid.org/0009-0003-4020-4892)
- Luciano Martínez Martínez
Institutions
- Complejo Hospitalario de Pontevedra (ES)
Publication Details
- Journal
- Annals of Pharmacotherapy
- Published
- 2026-01-03
- DOI
- https://doi.org/10.1177/10600280251407146
- Primary Topic
- Sphingolipid Metabolism and Signaling
- Type
- article
- Field-Weighted Citation Impact
- 0.00