Propofol Attenuates LPS-induced Inflammation by Suppressing the Activation of Histone Lactylation in hCMEC/D3 Cells

Propofol inhibits LPS-induced lactylation, ferroptosis, and release of inflammatory cytokines in hCMEC/D3 cells by downregulating the expression of LDHA.

Authors

Yaojun Lu (ORCID: https://orcid.org/0000-0002-6019-2687)
Xiaowei Ding
Xiangyuan Chen
Jiawei Chen

Institutions

Tongren Hospital (CN)
Obstetrics and Gynecology Hospital of Fudan University (CN)

Publication Details

Journal: Current Neurovascular Research
Published: 2025-09-01
DOI: https://doi.org/10.2174/0115672026423091251211090557
Primary Topic: Ferroptosis and cancer prognosis
Type: article
Field-Weighted Citation Impact: 0.00

Controls

|||

ALL TIME

JAN

FEB

MAR

APR

MAY

JUN

JUL

AUG

SEP

OCT

article

Propofol Attenuates LPS-induced Inflammation by Suppressing the Activation of Histone Lactylation in hCMEC/D3 Cells

Yaojun Lu, Xiaowei Ding, Xiangyuan Chen, Jiawei Chen

Sep 1, 2025

Current Neurovascular Research

Ferroptosis and cancer prognosis

article

Propofol Attenuates LPS-induced Inflammation by Suppressing the Activation of Histone Lactylation in hCMEC/D3 Cells

Yaojun Lu, Xiaowei Ding, Xiangyuan Chen, Jiawei Chen

September 1, 2025article en

Abstract

Propofol inhibits LPS-induced lactylation, ferroptosis, and release of inflammatory cytokines in hCMEC/D3 cells by downregulating the expression of LDHA.

Current Neurovascular ResearchVol. 22(4)

Tongren Hospital (CN), Obstetrics and Gynecology Hospital of Fudan University (CN)

Good health and well-being

Openalex Percentile: Top 26%

Ferroptosis and cancer prognosis

DOI Source OpenAlex

AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Propofol Attenuates LPS-induced Inflammation by Suppressing the Activation of Histone Lactylation in hCMEC/D3 Cells — Yaojun Lu, Xiaowei Ding, et al. · Current Neurovascular Research (2025) | TGRS Research Map | TGRS