Surgical Management of Digital Neuromas: A Systematic Review of Techniques, Outcomes, and Pain Relief

Surgical treatment of painful digital neuromas provides meaningful pain relief and functional improvement, particularly when techniques restore physiologic targets for regenerating axons rather than relying on excision alone. Continuity-restoring and reinnervation-based approaches, including neurorrhaphy, nerve capping, RPNI, and TMR, demonstrate favourable outcomes with lower recurrence rates, although comparative evidence remains limited. Standardised outcome measures and higher-quality comparative studies are required to guide optimal, patient-specific surgical decision-making.

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Journal
Hand
Published
2026-01-03
DOI
https://doi.org/10.1177/15589447251407141
Primary Topic
Nerve injury and regeneration
Type
article
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article

Surgical Management of Digital Neuromas: A Systematic Review of Techniques, Outcomes, and Pain Relief

Jennifer S. Novo, Warren M. Rozen, Ishith Seth, Omar Shadid et al.
Hand
Nerve injury and regeneration
article

Surgical Management of Digital Neuromas: A Systematic Review of Techniques, Outcomes, and Pain Relief

Jennifer S. Novo, Warren M. Rozen, Ishith Seth, Omar Shadid, Yi Mon, Raj Saini, Bryan Lim, Gianluca Marcaccini
article en

Abstract

Surgical treatment of painful digital neuromas provides meaningful pain relief and functional improvement, particularly when techniques restore physiologic targets for regenerating axons rather than relying on excision alone. Continuity-restoring and reinnervation-based approaches, including neurorrhaphy, nerve capping, RPNI, and TMR, demonstrate favourable outcomes with lower recurrence rates, although comparative evidence remains limited. Standardised outcome measures and higher-quality comparative studies are required to guide optimal, patient-specific surgical decision-making.

Hand
University of Siena (IT), Simon Fraser University (CA), Peninsula Health (AU)
Good health and well-being
Openalex Percentile: Top 97%
Nerve injury and regeneration
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Surgical Management of Digital Neuromas: A Systematic Review of Techniques, Outcomes, and Pain Relief — Jennifer S. Novo, Warren M. Rozen, et al. · Hand (2026) | TGRS Research Map | TGRS