Bronchoscopic cryobiopsy debulking of endobronchial myxoma—a rare presentation

Abstract Background Endobronchial myxomas are rare benign mesenchymal tumours, with only a handful number of cases reported in the medical literature. Case presentation We present the case of a 54-year-old Asian male, non-smoker, with a 6-month history of persistent dry cough. Clinical evaluation revealed decreased air entry in the left hemithorax. Imaging demonstrated a well-defined intraluminal mass in the left main bronchus causing near-complete obstruction and distal collapse. Spirometry showed moderate airflow obstruction without reversibility. Bronchoscopy identified a vascular lesion obstructing the left main bronchus. Initial partial debulking with electrocautery and cryobiopsy was performed under general anaesthesia due to intra-procedural hypoxia. Histopathology confirmed endobronchial myxoma. A repeat bronchoscopic procedure 3 weeks later achieved complete tumour removal and electrocautery ablation of the tumour base. Post-procedure recovery was uneventful, with full symptom resolution and lung re-expansion. Conclusion This case highlights the importance of considering rare benign tumours in patients with persistent respiratory symptoms and demonstrates the efficacy of minimally invasive bronchoscopic management.