Effects of cigarette smoke and HIV-1 factors on blood-brain barrier integrity and permeability in an in vitro model

CSE and TG serum induced separate and additive toxic effects on BBB function and integrity, which may underlie mechanisms that are associated with more severe HAND among HIV+ cigarette smokers.

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Publication Details

Journal
Journal of NeuroVirology
Published
2026-01-02
DOI
https://doi.org/10.1007/s13365-025-01295-2
Primary Topic
Barrier Structure and Function Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Effects of cigarette smoke and HIV-1 factors on blood-brain barrier integrity and permeability in an in vitro model

Binu Tharakan, Talib Saafir, Walter Royal, Joseph D. Walker
Journal of NeuroVirology
Barrier Structure and Function Studies
article

Effects of cigarette smoke and HIV-1 factors on blood-brain barrier integrity and permeability in an in vitro model

Binu Tharakan, Talib Saafir, Walter Royal, Joseph D. Walker
article en

Abstract

CSE and TG serum induced separate and additive toxic effects on BBB function and integrity, which may underlie mechanisms that are associated with more severe HAND among HIV+ cigarette smokers.

Journal of NeuroVirologyVol. 32(1)
Morehouse School of Medicine (US), Morgan State University (US)
Morehouse School of Medicine, National Institutes of Health
Good health and well-being
Openalex Percentile: Top 98%
Barrier Structure and Function Studies
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