Genomic landscape of metastatic breast cancers in young adults: a liquid biopsy analysis of women aged 20–40 years

ESCAT tiers I-III alterations were reported in 79 % YA with MBC which supports the role of molecular profiling in YA. The differences detected in the genomic profiles of YA with BC and older patients may allude to potential different underlying disease biology.

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Publication Details

Journal
The Breast
Published
2026-01-02
DOI
https://doi.org/10.1016/j.breast.2025.104690
Primary Topic
Breast Cancer Treatment Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Genomic landscape of metastatic breast cancers in young adults: a liquid biopsy analysis of women aged 20–40 years

Barbara Pistilli, F. Mosele, F. Giugliano, C. Nicotra et al.
The Breast
Breast Cancer Treatment Studies
article

Genomic landscape of metastatic breast cancers in young adults: a liquid biopsy analysis of women aged 20–40 years

Barbara Pistilli, F. Mosele, F. Giugliano, C. Nicotra, Thomas Grinda, Jean Zeghondy, Lauriane Minot, Cyril Roussel-Simonin, A.A. Viansone, Ernest Diab, Alexandre Xu-Vuillard, Julia R Dixon-Douglas, Alessandra Spata, T. Ben Ahmed, Elie Rassy, Martina Pagliuca, Joana Ribeiro, Antoine Italiano, Chayma Bousrih, Suzette Delaloge, Arnaud Bayle, Fabrice André
article en

Abstract

ESCAT tiers I-III alterations were reported in 79 % YA with MBC which supports the role of molecular profiling in YA. The differences detected in the genomic profiles of YA with BC and older patients may allude to potential different underlying disease biology.

The BreastVol. 85
Université de Bordeaux (FR), Inserm (FR), Université Paris-Saclay (FR), Peter MacCallum Cancer Centre (AU), Institut Gustave Roussy (FR), Institut Bergonié (FR)
Openalex Percentile: Top 98%
Breast Cancer Treatment Studies
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Genomic landscape of metastatic breast cancers in young adults: a liquid biopsy analysis of women aged 20–40 years — Barbara Pistilli, F. Mosele, et al. · The Breast (2026) | TGRS Research Map | TGRS