THC induced similar physiological effects on HIV transgenic rats and their controls without affecting HIV-induced deficits in effortful motivation

Hence, THC produces consistent physiological and motivational across HIV-1tg rats and their controls. Additionally, the HIV-1tg rat exhibited motivational deficits only when compared to the F344 but not WT controls, suggesting careful selections of control groups in future studies.

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Publication Details

Journal
Journal of Cannabis Research
Published
2026-01-02
DOI
https://doi.org/10.1186/s42238-025-00383-8
Primary Topic
Cannabis and Cannabinoid Research
Type
article
Field-Weighted Citation Impact
0.00
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article

THC induced similar physiological effects on HIV transgenic rats and their controls without affecting HIV-induced deficits in effortful motivation

Arpi Minassian, Samantha M. Ayoub, Sunitha Vemuri, Jared W. Young
Journal of Cannabis Research
Cannabis and Cannabinoid Research
article

THC induced similar physiological effects on HIV transgenic rats and their controls without affecting HIV-induced deficits in effortful motivation

Arpi Minassian, Samantha M. Ayoub, Sunitha Vemuri, Jared W. Young
article en

Abstract

Hence, THC produces consistent physiological and motivational across HIV-1tg rats and their controls. Additionally, the HIV-1tg rat exhibited motivational deficits only when compared to the F344 but not WT controls, suggesting careful selections of control groups in future studies.

Journal of Cannabis ResearchVol. 8(1)
University of California San Diego (US), VA San Diego Healthcare System (US)
Good health and well-being
Openalex Percentile: Top 97%
Cannabis and Cannabinoid Research
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