The Effects of Selective Serotonin Reuptake Inhibitors on Motility of Peripheral Smooth Muscles

Abstract According to the World Health Organization, part of the quality of life is the perception of one's body concerning the culture and values of each individual. Limb amputation affects the quality of life through several defined aspects. Observing the available statistical data, after the amputation of the lower extremities, only 65% survived the first year, 52% survived the first two years, 37% survived three years, and five or more years, only up to 15% of patients with amputated limbs. Epidemiological data on the frequency of lower limb amputations are pretty similar to those in developed countries. Modern prostheses enable daily use, intending to replace the missing limb. Many factors influence the outcome of rehabilitation treatment and the result of functional recovery. Among the factors that influence the favorable outcome of rehabilitation and independence in activities of daily living is the level of amputation, age, and comorbidities. For patients after amputation of the lower extremities, the goal in rehabilitation is to achieve as much independence as possible within the activities of daily life. Our study aimed to examine daily functionality and activity through the Barthel and functional independence indices-FIM tests during post-operative rehabilitation and after one month.