Repression of Polycomb Group Factor 1 Inhibits EMT Progression in Colon Cancers Cells via Wnt/β-Catenin and PI3K/Akt/mTOR Signaling Pathway

PCGF1 may promote the proliferation and EMT process in HCT116 and HT29 cells by activating the Wnt/β-catenin and PI3K/Akt/mTOR signaling pathway.

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Publication Details

Journal
Digestive Diseases and Sciences
Published
2026-01-03
DOI
https://doi.org/10.1007/s10620-025-09641-4
Primary Topic
Cancer Cells and Metastasis
Type
article
Field-Weighted Citation Impact
0.00
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article

Repression of Polycomb Group Factor 1 Inhibits EMT Progression in Colon Cancers Cells via Wnt/β-Catenin and PI3K/Akt/mTOR Signaling Pathway

Junhong Wang, Peng An, Rong Fan
Digestive Diseases and Sciences
Cancer Cells and Metastasis
article

Repression of Polycomb Group Factor 1 Inhibits EMT Progression in Colon Cancers Cells via Wnt/β-Catenin and PI3K/Akt/mTOR Signaling Pathway

Junhong Wang, Peng An, Rong Fan
article en

Abstract

PCGF1 may promote the proliferation and EMT process in HCT116 and HT29 cells by activating the Wnt/β-catenin and PI3K/Akt/mTOR signaling pathway.

Digestive Diseases and Sciences
Tianjin University of Commerce (CN), Tianjin University of Traditional Chinese Medicine (CN), Tianjin Central Hospital of Gynecology Obstetrics (CN)
Good health and well-being
Openalex Percentile: Top 99%
Cancer Cells and Metastasis
DOIOpen Access PDFOpenAlex
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