Research on liver cancer pathology image recognition based on deep learning image processing

The accurate diagnosis of Liver cancer through pathological image analysis remains challenging due to the complexity and heterogeneity of histopathological features. This study proposes MSAF-Net, a novel multi-space attention fusion network that systematically integrates five complementary feature spaces (R, B, Y, entropy, and LBP) with an SE-block enhanced fusion mechanism and EfficientNet-Lite based feature extraction. The proposed framework establishes a new state-of-the-art in pathological image analysis by effectively combining engineered feature spaces with deep learning, offering both high diagnostic reliability and computational efficiency for clinical applications. Experimental results demonstrate superior performance with 94.7% accuracy, 93.2% sensitivity, and 95.8% specificity, representing significant improvements of 6.3%, 7.1%, and 5.6% respectively over conventional single-space methods.

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Publication Details

Journal
Scientific Reports
Published
2026-01-02
DOI
https://doi.org/10.1038/s41598-025-24834-7
Primary Topic
AI in cancer detection
Type
article
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article

Research on liver cancer pathology image recognition based on deep learning image processing

Huanzhang Niu, Mingyuan Yang
Scientific Reports
AI in cancer detection
article

Research on liver cancer pathology image recognition based on deep learning image processing

Huanzhang Niu, Mingyuan Yang
article en

Abstract

The accurate diagnosis of Liver cancer through pathological image analysis remains challenging due to the complexity and heterogeneity of histopathological features. This study proposes MSAF-Net, a novel multi-space attention fusion network that systematically integrates five complementary feature spaces (R, B, Y, entropy, and LBP) with an SE-block enhanced fusion mechanism and EfficientNet-Lite based feature extraction. The proposed framework establishes a new state-of-the-art in pathological image analysis by effectively combining engineered feature spaces with deep learning, offering both high diagnostic reliability and computational efficiency for clinical applications. Experimental results demonstrate superior performance with 94.7% accuracy, 93.2% sensitivity, and 95.8% specificity, representing significant improvements of 6.3%, 7.1%, and 5.6% respectively over conventional single-space methods.

Scientific ReportsVol. 16(1)
First Affiliated Hospital of Henan University of Science and Technology (CN)
Openalex Percentile: Top 97%
AI in cancer detection
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