A sensor-fault resilient artificial pancreas using type-3 fuzzy logic and predictive controls

We propose a fault-tolerant artificial pancreas architecture for type 1 diabetes management that leverages advanced artificial intelligence (AI) methods. The system combines a step-forward predictive controller with a type-3 fuzzy logic system (FLS) in a dual-loop structure, augmented by a real-time sensor fault detection and compensation unit. The fault detection unit uses fuzzy prediction to estimate and correct sensor fault coefficients, thereby mitigating the impact of corrupted glucose measurements. Closed-loop stability is established through Lyapunov-based analysis, which informs the design of the adaptive compensator. Performance was evaluated using simulation studies on a modified Bergman model that incorporates patient variability and external disturbances. Results show that the proposed AI-based controller achieves greater robustness, adaptability, and fault tolerance compared with conventional control approaches. These findings demonstrate the promise of integrating predictive control with fuzzy logic for reliable intelligent healthcare systems, offering new opportunities for safe and effective AI-driven solutions in biomedical engineering.

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Publication Details

Journal
Scientific Reports
Published
2026-01-02
DOI
https://doi.org/10.1038/s41598-025-34383-8
Primary Topic
Diabetes Management and Research
Type
article
Field-Weighted Citation Impact
0.00
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article

A sensor-fault resilient artificial pancreas using type-3 fuzzy logic and predictive controls

Ali Khani, Ardashir Mohammadzadeh, Khalid A. Alattas, Venkata Siva Nageswararao T
Scientific Reports
Diabetes Management and Research
article

A sensor-fault resilient artificial pancreas using type-3 fuzzy logic and predictive controls

Ali Khani, Ardashir Mohammadzadeh, Khalid A. Alattas, Venkata Siva Nageswararao T
article en

Abstract

We propose a fault-tolerant artificial pancreas architecture for type 1 diabetes management that leverages advanced artificial intelligence (AI) methods. The system combines a step-forward predictive controller with a type-3 fuzzy logic system (FLS) in a dual-loop structure, augmented by a real-time sensor fault detection and compensation unit. The fault detection unit uses fuzzy prediction to estimate and correct sensor fault coefficients, thereby mitigating the impact of corrupted glucose measurements. Closed-loop stability is established through Lyapunov-based analysis, which informs the design of the adaptive compensator. Performance was evaluated using simulation studies on a modified Bergman model that incorporates patient variability and external disturbances. Results show that the proposed AI-based controller achieves greater robustness, adaptability, and fault tolerance compared with conventional control approaches. These findings demonstrate the promise of integrating predictive control with fuzzy logic for reliable intelligent healthcare systems, offering new opportunities for safe and effective AI-driven solutions in biomedical engineering.

Scientific ReportsVol. 16(1)
Sakarya University (TR), Ton Duc Thang University (VN), University of Tabriz (IR), University of Jeddah (SA)
Openalex Percentile: Top 98%
Diabetes Management and Research
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A sensor-fault resilient artificial pancreas using type-3 fuzzy logic and predictive controls — Ali Khani, Ardashir Mohammadzadeh, et al. · Scientific Reports (2026) | TGRS Research Map | TGRS