New Perspectives on Stroke: The Immune-inflammatory-mitochondrial Axis

Our study delineates a distinct immune-inflammatory-mitochondrial axis in stroke, characterized by predominant CD4+ involvement in AIS versus CD8+ T-cell alterations in ICH. These findings underscore the potential for immunomodulatory and mitochondrial-protective strategies tailored to specific stroke subtypes.

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Publication Details

Journal
Current Neurovascular Research
Published
2025-12-01
DOI
https://doi.org/10.2174/0115672026420631251201053456
Primary Topic
Neuroinflammation and Neurodegeneration Mechanisms
Type
article
Field-Weighted Citation Impact
0.00
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article

New Perspectives on Stroke: The Immune-inflammatory-mitochondrial Axis

Yingyu Li, Biqiong Ren, Yiyi Peng, Yang Xu et al.
Current Neurovascular Research
Neuroinflammation and Neurodegeneration Mechanisms
article

New Perspectives on Stroke: The Immune-inflammatory-mitochondrial Axis

Yingyu Li, Biqiong Ren, Yiyi Peng, Yang Xu, Jiajin Chen
article en

Abstract

Our study delineates a distinct immune-inflammatory-mitochondrial axis in stroke, characterized by predominant CD4+ involvement in AIS versus CD8+ T-cell alterations in ICH. These findings underscore the potential for immunomodulatory and mitochondrial-protective strategies tailored to specific stroke subtypes.

Current Neurovascular ResearchVol. 22(5)
Hunan University of Traditional Chinese Medicine (CN), Changsha Medical University (CN), Second People Hospital of Hunan (CN)
Openalex Percentile: Top 36%
Neuroinflammation and Neurodegeneration Mechanisms
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