Hypoxia-induced exosomal circ_0006840 promotes pancreatic cancer progress by regulating the WIF1 decay

It has been shown that circ_0006840 was transcriptionally activated by HIF1A and specifically regulated WIF1 transcripts, which is considered a potential target for PC therapy.

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Publication Details

Journal
BMC Biology
Published
2026-01-02
DOI
https://doi.org/10.1186/s12915-025-02320-w
Primary Topic
Circular RNAs in diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Hypoxia-induced exosomal circ_0006840 promotes pancreatic cancer progress by regulating the WIF1 decay

Zhiwei He, Wenpeng Cao, Yating Sun, Yufeng Hu et al.
BMC Biology
Circular RNAs in diseases
article

Hypoxia-induced exosomal circ_0006840 promotes pancreatic cancer progress by regulating the WIF1 decay

Zhiwei He, Wenpeng Cao, Yating Sun, Yufeng Hu, Zhixue Zhang, Shan Lei
article en

Abstract

It has been shown that circ_0006840 was transcriptionally activated by HIF1A and specifically regulated WIF1 transcripts, which is considered a potential target for PC therapy.

BMC BiologyVol. 24(1)
Guiyang Medical University (CN), Affiliated Hospital of Guizhou Medical University (CN), Shenzhen University Health Science Center (CN)
Good health and well-being
Openalex Percentile: Top 98%
Circular RNAs in diseases
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